Veterinary OTC

 [Veterinary Drug Name]

Generic name: Albendazole and Ivermectin Tablets

Trade name:

English name: Albendazole and Ivermectin Tablets

Pinyin: Abendazuo Yiweijunsu Pian

         [Main Ingredients] Albendazole, ivermectin

         [Description] This drug is of white or off-white tablets.

        [Pharmacological Action] Antiparasitic agent. Albendazole has broad-spectrum anthelmintic activity and can kill nematodes, tapeworms and trematodes. Its mechanism of action is to bind to microtubule proteins in the helminth and prevent it from polymerizing with α-microtubule protein to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism in the helminth.

        Ivermectin has a good anthelmintic and killing effect on entozoic and epizoic parasites, especially arthropod insects and entozoic nematodes, and it is mainly used to expel gastrointestinal nematodes, lungworms and epizoic parasites in cattle, sheep and other animals. Its anthelmintic mechanism is to promote the release of γ-aminobutyric acid (GABA) from presynaptic neurons, thus opening the GABA-mediated chloride ion channel. The chloride ion flow can reduce the impedance of the cell membrane and result in a slight depolarization of the rest potential of the postsynaptic membrane, thereby interfering with inter-neuromuscular signal transmission, causing the worms to relax and paralyze and further killing and expelling them from the body.

        [Function and Use] Anthelmintic, for expelling or killing nematodes, trematodes, tapeworms, mites and other entozoic and epizoic parasites in cattle and sheep.

        [Dosage and Administration] Oral administration: 0.3 tablets/time per 10kg of body weight for cattle and sheep.

        [Adverse Reaction] No adverse reactions have been observed with the proper use of the recommended dosage and administration.

        [Precautions] (1) It is prohibited during lactation period.

(2) Ivermectin is this drug is highly toxic to fish and shrimps and the residue, package and animal excrements should be prevented from contaminating water sources.

       [Withdrawal Period] 35 days for cattle and sheep.

       [Specification] 0.36g (350mg albendazole + 10mg ivermectin)

       [Package] 100 tablets/bottle × 60 bottles/carton

       [Storage] It should be sealed in a cool and dark place for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080196059

[Executive Standard] Chemical Drug Volume of Veterinary Drug Quality Standard (2017 Edition)