Veterinary OTC

[Veterinary Drug Name]

Generic name: Fenbendazole and Ivermectin Tablets

Trade name: Fenyi

English name: Fenbendazole and Ivermectin Tablets

Pinyin: Fenbendazuo Yiweijunsu Pian

[Main Ingredients] Fenbendazole, ivermectin

[Description] This drug is of white or off-white tablets.

[Pharmacological Action] Antihelmintic. Fenbendazole has broad-spectrum anthelmintic activity and can kill nematodes, tapeworms and trematodes. Its mechanism of action is to bind to microtubule proteins in the helminth, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism in the helminth.

Ivermectin has a good anthelmintic and killing effect on entozoic and epizoic parasites, especially arthropods and entozoic nematodes, and it is mainly used to expel gastrointestinal nematodes, lungworms and epizoic parasites in cattle, sheep and other animals. Its anthelmintic mechanism is to promote the release of γ-aminobutyric acid (GABA) from presynaptic neurons, thus opening the GABA-mediated chloride ion channel. The chloride ion flow can reduce the impedance of the cell membrane and result in a slight depolarization of the rest potential of the postsynaptic membrane, thereby interfering with inter-neuromuscular signal transmission, causing the worms to paralyze and further killing and expelling them from the body.

[Function and Use] Antihelmintic, for the treatment of nematodiasis, cestodiasis and acariasis in cattle, sheep and pigs.

[Dosage and Administration] Oral administration: 0.25-0.375 tablets/time per 10kg of body weight for cattle, sheep and pigs.

[Adverse Reaction] No adverse reactions have been observed with the proper use of the recommended dosage and administration.

[Precautions] (1) It is prohibited during lactation period.

(2)Ivermectin is highly toxic to shrimps, fish and aquatic organisms, and the packaging and containers of residual drugs should be prevented from contaminating water sources.

(3)Administration with caution within the first 45 days during pregnancy.

[Withdrawal Period] 35 days for cattle and sheep, and 28 days for pigs.

[Specification] 0.210g (0.2g fenbendazole + 10mg ivermectin)

[Package] 100 tablets/bottle × 60 bottles/carton

[Storage] It should be kept out of light and sealed for storage.

[Shelf Life] 2 years

[Production License No.] (2022) SYSCZZ No. 08019

[GMP Certificate No.] (2022) SY GMP ZZ No. 08010

[Approval No.] SYZ No. 080196438

[Executive Standard] Chemical Drug Volume of Veterinary Drug Quality Standard (2017 Edition)